BDBM50277197 CHEMBL4170544

SMILES O=C(C1CCCCC1)N1CC2C(C1)C1C=CC2C2CC12

InChI Key InChIKey=XEKLWKJPULBVKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50277197   

Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50277197(CHEMBL4170544)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human full-length 11beta-HSD2 expressed in HEK293 cells using cortisol as substrate after 2 hrs by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50277197(CHEMBL4170544)
Affinity DataIC50: 20nMAssay Description:Inhibition of 11beta-HSD1 in human liver microsomes using [3H]cortisone as substrate preincubated for 15 mins followed by substrate addition and meas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/29/2020
Entry Details Article
PubMed