BDBM50276785 CHEMBL4164185

SMILES Fc1ccc(cc1)-c1cccc2c(-c3ccc(F)cc3)c(-c3ccc(F)cc3)c(nc12)C(F)(F)F

InChI Key InChIKey=VPWOHPAMQAAGLG-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50276785   

LigandPNGBDBM50276785(CHEMBL4164185)
Affinity DataIC50: 510nMAssay Description:Inhibition of human full length NPP1 expressed in African green monkey COS7 cell membrane fraction using p-nitrophenyl-5'-thymidine monophosphate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Human)
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276785(CHEMBL4164185)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
LigandPNGBDBM50276785(CHEMBL4164185)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human full length NPP3 expressed in African green monkey COS7 cell membrane fraction using p-nitrophenyl-5'-thymidine monophosphate as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Human)
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276785(CHEMBL4164185)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 3(Human)
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276785(CHEMBL4164185)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase3 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed
TargetEctonucleoside triphosphate diphosphohydrolase 8(Human)
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276785(CHEMBL4164185)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed