BDBM50276757 CHEMBL4168235

SMILES COc1cc2c(Nc3ccc(cc3)C#N)ncnc2cc1OCCCN1CCC(CC1)c1ccccc1

InChI Key InChIKey=AJLOXRITXPRKIC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276757   

TargetEpidermal growth factor receptor(Human)
Beijing Normal University

Curated by ChEMBL
LigandPNGBDBM50276757(CHEMBL4168235)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of recombinant human His-tagged EGFR (1 to 645 residues) expressed in HEK293 cells using Tyr66-biotinylated PTP1B peptide as substrate pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/25/2020
Entry Details Article
PubMed