BDBM50276374 CHEMBL4126946

SMILES OC[C@H]1OCC(=O)C[C@@H]1O

InChI Key InChIKey=ATVAXTJIRCBICU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50276374   

TargetNACHT, LRR and PYD domains-containing protein 3(Human)
The Noguchi Institute

Curated by ChEMBL
LigandPNGBDBM50276374(CHEMBL4126946)
Affinity DataIC50: 2.30E+6nMAssay Description:Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed
TargetNACHT, LRR and PYD domains-containing protein 3(Mouse)
The Noguchi Institute

Curated by ChEMBL
LigandPNGBDBM50276374(CHEMBL4126946)
Affinity DataIC50: 1.60E+6nMAssay Description:Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2020
Entry Details Article
PubMed