BDBM50275922 (S)-2-(4-chlorophenoxy)-3-(4-phenoxyphenyl)propanoic acid::CHEMBL472245

SMILES OC(=O)[C@H](Cc1ccc(Oc2ccccc2)cc1)Oc1ccc(Cl)cc1

InChI Key InChIKey=MSSRKTSVXGKBDH-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50275922   

LigandPNGBDBM50275922((S)-2-(4-chlorophenoxy)-3-(4-phenoxyphenyl)propano...)
Affinity DataEC50:  870nMAssay Description:Agonist activity at human PPARgamma ligand binding domain expressed in human HepG2 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275922((S)-2-(4-chlorophenoxy)-3-(4-phenoxyphenyl)propano...)
Affinity DataEC50:  27nMAssay Description:Agonist activity at human PPARalpha ligand binding domain expressed in human HepG2 cells co-transfected with Gal4 by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275922((S)-2-(4-chlorophenoxy)-3-(4-phenoxyphenyl)propano...)
Affinity DataEC50:  3.90E+3nMAssay Description:Agonist activity at GAL4-fused PPARalpha (unknown origin) expressed in human HepG2 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
LigandPNGBDBM50275922((S)-2-(4-chlorophenoxy)-3-(4-phenoxyphenyl)propano...)
Affinity DataEC50:  320nMAssay Description:Agonist activity at GAL4-fused PPARgamma (unknown origin) expressed in human HepG2 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
LigandPNGBDBM50275922((S)-2-(4-chlorophenoxy)-3-(4-phenoxyphenyl)propano...)
Affinity DataEC50:  900nMAssay Description:Agonist activity at GAL4-fused PPARalpha A454M mutant (unknown origin) expressed in human HepG2 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
LigandPNGBDBM50275922((S)-2-(4-chlorophenoxy)-3-(4-phenoxyphenyl)propano...)
Affinity DataEC50:  320nMAssay Description:Agonist activity at GAL4-fused PPARgamma (unknown origin) expressed in human HepG2 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
LigandPNGBDBM50275922((S)-2-(4-chlorophenoxy)-3-(4-phenoxyphenyl)propano...)
Affinity DataEC50:  3.90E+3nMAssay Description:Agonist activity at GAL4-fused PPARalpha (unknown origin) expressed in human HepG2 cells by transactivation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed