BDBM50275675 CHEMBL519738::N-(2-chlorobenzyl)-5-(2,2,2-trifluoroacetyl)thiophene-2-carboxamide

SMILES FC(F)(F)C(=O)c1ccc(s1)C(=O)NCc1ccccc1Cl

InChI Key InChIKey=DZVLJOBRBUAXRO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275675   

TargetHistone deacetylase 1(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50275675(N-(2-chlorobenzyl)-5-(2,2,2-trifluoroacetyl)thioph...)
Affinity DataIC50: 550nMAssay Description:Inhibition of HDAC1 purified from HEK293 cells by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Irbm-Merck Research Laboratories Rome

Curated by ChEMBL
LigandPNGBDBM50275675(N-(2-chlorobenzyl)-5-(2,2,2-trifluoroacetyl)thioph...)
Affinity DataIC50: 190nMAssay Description:Inhibition of HDAC6 purified from HEK293 cells by Western blotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed