BDBM50275560 4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-1-yl)-N-(3-(trifluoromethylthio)phenyl)-1,4'-bipiperidine-1'-carboxamide::CHEMBL487986

SMILES FC(F)(F)Sc1cccc(NC(=O)N2CCC(CC2)N2CCC(CC2)n2c3ccc(Cl)cc3[nH]c2=O)c1

InChI Key InChIKey=GIWVDIDTRYDGRF-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50275560   

TargetMuscarinic acetylcholine receptor M5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50275560(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at muscarinic M5 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50275560(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50275560(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at muscarinic M2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M3(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50275560(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at muscarinic M3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M4(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50275560(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at muscarinic M4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50275560(4-(5-chloro-2-oxo-2,3-dihydro-1H-benzo[d]imidazol-...)
Affinity DataEC50:  3.60E+3nMAssay Description:Agonist activity at muscarinic M1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed