BDBM50274894 (Z)-5-(Naphthalen-1'-ylmethylene)-2-thioxothiazolidin-4-one::(Z)-5-(Naphthalen-1-ylmethylene)-2-thioxothiazolidin-4-one::CHEMBL457747

SMILES SC1=NC(=O)C(S1)=Cc1cccc2ccccc12

InChI Key InChIKey=KHWBBJGNDBRXEW-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50274894   

TargetArylamine N-acetyltransferase 2(Mouse)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50274894((Z)-5-(Naphthalen-1-ylmethylene)-2-thioxothiazolid...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of mouse recombinant NAT2 assessed as hydrolysis of acetyl coA using PABA as substrate by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member B1 [K65Q](Bovine)
University of Messina

Curated by ChEMBL
LigandPNGBDBM50274894((Z)-5-(Naphthalen-1-ylmethylene)-2-thioxothiazolid...)
Affinity DataIC50: 2.27E+3nMAssay Description:Inhibition of bovine lens aldose reductase assessed as inhibition of NDAPH oxidation by non-linear regression analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50274894((Z)-5-(Naphthalen-1-ylmethylene)-2-thioxothiazolid...)
Affinity DataIC50: 62nMAssay Description:Inhibition of recombinant PIM1 (unknown origin) by pyruvate kinase/lactate dehydrogenase-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/15/2019
Entry Details Article
PubMed