BDBM50273883 CHEMBL460174::beta-Chloro-alpha-methylcinnamaldehyde guanylhydrazone

SMILES [#6]-[#6](-[#6]=[#7]\[#7]=[#6](\[#7])-[#7])=[#6](Cl)-c1ccccc1

InChI Key InChIKey=NSDQTAPJRTWXIB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273883   

TargetEstrogen receptor(Human)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273883(beta-Chloro-alpha-methylcinnamaldehyde guanylhydra...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC binding to recombinant estrogen receptor by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGag polyprotein(Avian erythroblastosis virus (strain ES4))
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273883(beta-Chloro-alpha-methylcinnamaldehyde guanylhydra...)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at estrogen receptor alpha expressed in human HEC1 cells assessed as inhibition of 1 nM estradiol-induced transcriptional activit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEnvelope glycoprotein gp70(MMTV)
University of Illinois At Urbana-Champaign

Curated by ChEMBL
LigandPNGBDBM50273883(beta-Chloro-alpha-methylcinnamaldehyde guanylhydra...)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of estradiol-induced coactivator peptide SRC1 binding to estrogen receptor alpha expressed in human HEC1 cells after 24 hrs by luciferase ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed