BDBM50273551 CHEMBL4129143::US11535607, Example 45-1

SMILES ONC(=O)c1cccc2CN(Cc12)c1ccc(cn1)C(F)(F)F

InChI Key InChIKey=IPSMKDVVNSAVIF-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50273551   

TargetHistone deacetylase 11(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273551(CHEMBL4129143 | US11535607, Example 45-1)
Affinity DataIC50: 7nMAssay Description:Inhibition of full length recombinant human HDAC11 expressed in baculoviral expression system using FAM-RHKK as substrate by electrophoretic mobility...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistone deacetylase 11(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273551(CHEMBL4129143 | US11535607, Example 45-1)
Affinity DataIC50: 500nMAssay Description:The probe binding HDAC11 assay was performed using a time resolved fluorescence (TRF) assay format. Recombinant N-terminal GST tag full-length human ...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetHistone deacetylase 11(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50273551(CHEMBL4129143 | US11535607, Example 45-1)
Affinity DataIC50: 500nMAssay Description:The measurement of HD AC 11 deacetylase activity was performed using an electrophoretic mobility shift assay by Nanosyn (Santa Clara, Calif.). Full l...More data for this Ligand-Target Pair
In DepthDetails
US Patent