BDBM50272955 CHEMBL4129001

SMILES NC(=O)c1ccc(Oc2cccc(c2)C(=O)N2CCN(CC2)c2ccc(F)cc2)cc1

InChI Key InChIKey=MFXVNPUAZXWGLT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272955   

TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272955(CHEMBL4129001)
Affinity DataIC50: 1.35E+3nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272955(CHEMBL4129001)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272955(CHEMBL4129001)
Affinity DataIC50: 1.91E+4nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272955(CHEMBL4129001)
Affinity DataIC50: 780nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272955(CHEMBL4129001)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272955(CHEMBL4129001)
Affinity DataIC50: 776nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP14 WWA/catalytic domain expressed in Escherichia coli BL21(DE3) preincubated for 15 mins ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed