BDBM50272865 1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-((S)-2-methylcyclohexylidene)hydrazine::CHEMBL1242992::CHEMBL497675

SMILES C[C@H]1CCCCC1=NNc1nc(cs1)-c1ccc(F)cc1F

InChI Key InChIKey=GBSDYRSNVCORPF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272865   

TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50272865(CHEMBL497675 | CHEMBL1242992 | 1-(4-(2,4-difluorop...)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50272865(CHEMBL497675 | CHEMBL1242992 | 1-(4-(2,4-difluorop...)
Affinity DataIC50: 36.1nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50272865(CHEMBL497675 | CHEMBL1242992 | 1-(4-(2,4-difluorop...)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50272865(CHEMBL497675 | CHEMBL1242992 | 1-(4-(2,4-difluorop...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50272865(CHEMBL497675 | CHEMBL1242992 | 1-(4-(2,4-difluorop...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50272865(CHEMBL497675 | CHEMBL1242992 | 1-(4-(2,4-difluorop...)
Affinity DataIC50: 4.81E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed