BDBM50272570 CHEMBL4129844

SMILES COc1ccc2c(N[C@H](C)Cc3cc(C)[nH]n3)ncnc2c1OC

InChI Key InChIKey=JTROLECZHRVLFM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50272570   

LigandPNGBDBM50272570(CHEMBL4129844)
Affinity DataIC50: 579nMAssay Description:Inhibition of full length recombinant human PDE1C using 3',5'-[3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50272570(CHEMBL4129844)
Affinity DataIC50: 777nMAssay Description:Inhibition of full length recombinant human PDE1A using 3',5'-[3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50272570(CHEMBL4129844)
Affinity DataIC50: 596nMAssay Description:Inhibition of full length recombinant human PDE1B1 using 3',5'-[3H]cAMP as substrate after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50272570(CHEMBL4129844)
Affinity DataIC50: 596nMAssay Description:Inhibition of recombinant full length PDE1B in human myocardium using cAMP as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed