BDBM50272222 CHEMBL4128356

SMILES NC(=N)c1cccc(C[C@H](NS(=O)(=O)c2ccc3ccccc3c2)C(=O)N2CCCC(C2)C(=O)NCc2cccs2)c1

InChI Key InChIKey=PIFQUSTVOQWPJQ-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50272222   

TargetSerine protease hepsin(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272222(CHEMBL4128356)
Affinity DataIC50: 676nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272222(CHEMBL4128356)
Affinity DataIC50: 2.43E+3nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human uPA (M1 to L431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272222(CHEMBL4128356)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human Hepsin (R45 to L17 residues) D161E/ R162K double mutant expressed in mouse NS0 cells using Bo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50272222(CHEMBL4128356)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of recombinant C-terminal His10-tagged human uPA (M1 to L431 residues) expressed in mouse NS0 cells using Z-GGR-AMC as substrate after 15 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/1/2020
Entry Details Article
PubMed
TargetPlasminogen(Human)
Philipps University Marburg

Curated by ChEMBL
LigandPNGBDBM50272222(CHEMBL4128356)
Affinity DataKi:  140nMAssay Description:Inhibition of human plasminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMed