BDBM50271900 6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-[6-(trifluoromethoxy)-benzothiazol-2-ylamino]-quinoline-3-carbonitrile::CHEMBL499120

SMILES COc1cc2c(Nc3nc4ccc(OCC(F)(F)F)cc4s3)c(cnc2cc1OCCCN1CCN(C)CC1)C#N

InChI Key InChIKey=ZNXQFQLJQYSVNJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271900   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271900(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)
Affinity DataIC50: 178nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271900(6-Methoxy-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4...)
Affinity DataIC50: 6.56E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed