BDBM50271898 6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-(1H-benzimidazole-2-ylamino)-quinoline-3-carbonitrile::CHEMBL526135

SMILES CN1CCN(CCCOc2cc3ncc(C#N)c(Nc4nc5ccccc5[nH]4)c3cc2C)CC1

InChI Key InChIKey=CNSPDJCKWOBPKV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271898   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271898(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant cSrc by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50271898(6-Methyl-7-[3-(4-methylpiperazin-1-yl)-propoxy]-4-...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of inducible nitric oxide synthetase in LPS-stimulated mouse ANA1 macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/16/2012
Entry Details Article
PubMed