BDBM50271747 CHEMBL4127245

SMILES CC(C)c1cc(ccc1C(O)=O)-c1c[nH]c2ncc(cc12)-c1ccccc1

InChI Key InChIKey=SQQCNWHVXWEWKZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271747   

TargetCalcium/calmodulin-dependent protein kinase kinase 2(Mouse)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271747(CHEMBL4127245)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of CAMKK2 in mouse N39 cells assessed as decrease in AMPKalpha phosphorylation at T172 preincubated for 80 mins followed by inomycin addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271747(CHEMBL4127245)
Affinity DataIC50: 4nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/29/2020
Entry Details Article
PubMed