BDBM50271685 CHEMBL4128887

SMILES CC(C)C[C@H](N[C@@H](c1ccc(F)cc1)C(F)(F)F)C(=O)NC1(CC1)C#N

InChI Key InChIKey=AEMUDLMOFLXUQI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271685   

TargetProcathepsin L(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271685(CHEMBL4128887)
Affinity DataIC50: 84nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed
TargetToxopain-2(Toxoplasma gondii)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50271685(CHEMBL4128887)
Affinity DataIC50: 160nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2020
Entry Details Article
PubMed