BDBM50271463 (R)-2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-4-yl)-2-methylpropanamido)cyclohex-1-enecarboxylic acid::CHEMBL483934

SMILES C[C@H](Cc1cnn(c1C)-c1ccc(O)cc1)C(=O)NC1=C(CCCC1)C(O)=O

InChI Key InChIKey=TZGGJKMAPZGDSV-UHFFFAOYSA-N

Data  5 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50271463   

TargetCytochrome P450 2C8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50271463((R)-2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50271463((R)-2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50271463((R)-2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50271463((R)-2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50271463((R)-2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-...)
Affinity DataEC50:  350nMAssay Description:Displacement of [3H]niacin from GRP109A receptor in presence of 4% human serumMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHydroxycarboxylic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50271463((R)-2-(3-(1-(4-hydroxyphenyl)-5-methyl-1H-pyrazol-...)
Affinity DataIC50: 26nMAssay Description:Displacement of [3H]niacin from GRP109A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed