BDBM50271140 9-[(3-{4-[(5,6-Dimethoxy-1-oxoindan-2-yl)methyl]piperidin-1-yl}propyl)amino]-1,2,3,4-tetrahydroacridine dihydrochloride::CHEMBL460370

SMILES COc1cc2CC(CC3CCN(CCCNc4c5CCCCc5nc5ccccc45)CC3)C(=O)c2cc1OC

InChI Key InChIKey=IWFRXMAENNIBJM-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50271140   

TargetAcetylcholinesterase(Bovine)
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)

Curated by ChEMBL
LigandPNGBDBM50271140(9-[(3-{4-[(5,6-Dimethoxy-1-oxoindan-2-yl)methyl]pi...)
Affinity DataIC50: 0.290nMAssay Description:Inhibition of bovine erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)

Curated by ChEMBL
LigandPNGBDBM50271140(9-[(3-{4-[(5,6-Dimethoxy-1-oxoindan-2-yl)methyl]pi...)
Affinity DataIC50: 0.880nMAssay Description:Inhibition of human erythrocyte AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
Laboratori De Qu�Mica Farmac�Utica (Unitat Associada Al Csic)

Curated by ChEMBL
LigandPNGBDBM50271140(9-[(3-{4-[(5,6-Dimethoxy-1-oxoindan-2-yl)methyl]pi...)
Affinity DataIC50: 12.3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed