BDBM50270390 CHEMBL4062419

SMILES COc1cc2CN(C)CCc2cc1OCc1ccccc1

InChI Key InChIKey=AOTCQDVTCSQOEW-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50270390   

TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270390(CHEMBL4062419)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in HEK293 cells co-expressing Ric-3/NACHO assessed as inhibition of ACh-induced calcium mobilizat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270390(CHEMBL4062419)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up to...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit beta-2/beta-4(Mouse)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270390(CHEMBL4062419)
Affinity DataIC50: 2.40E+4nMAssay Description:Antagonist activity at mouse alpha4beta2 nAChR expressed in HEK293 cells assessed as inhibition of (S)-nicotine-induced current response measured up ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270390(CHEMBL4062419)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta2 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270390(CHEMBL4062419)
Affinity DataKi:  3.00E+5nMAssay Description:Displacement of [3H]epibatidine from rat alpha3beta4 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-4(Rat)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50270390(CHEMBL4062419)
Affinity DataKi:  3.00E+5nMAssay Description:Displacement of [3H]epibatidine from rat alpha4beta4 nAChR expressed in HEK293 cell membranes after 4 hrs by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed