BDBM50269299 CHEMBL4077072

SMILES O=C1C(C(=O)c2c1c(-c1ccccc1)c(-c1ccccc1)c(-c1ccc(Sc3ccc(cc3)-c3c(c4C(=O)N(C(=O)c4c(-c4ccccc4)c3-c3ccccc3)c3cccc(c3)C#N)-c3ccccc3)cc1)c2-c1ccccc1)c1cccc(c1)C#N

InChI Key InChIKey=FNPJCDRMPWNGMO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50269299   

TargetProstaglandin E synthase(Human)
University of Kentucky

Curated by ChEMBL
LigandPNGBDBM50269299(CHEMBL4077072)
Affinity DataIC50: 439nMAssay Description:Inhibition of human mPGES-1 expressed in 293-F cells using PGH2 as substrate preincubated for 15 mins followed by substrate addition measured after 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/10/2020
Entry Details Article
PubMed