BDBM50269119 CHEMBL4080898

SMILES FC(F)(F)c1cccnc1-c1cccc(c1)C(=O)Nc1cccc(c1-c1cccnn1)C(F)(F)F

InChI Key InChIKey=HZTAEIFNSFFSPA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50269119   

LigandPNGBDBM50269119(CHEMBL4080898)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human NaV1.5 expressed in HEK293 cells at -50 mV holding potential after 3 to 5 mins by PatchXpress automated electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed
LigandPNGBDBM50269119(CHEMBL4080898)
Affinity DataIC50: 510nMAssay Description:Inhibition of slow inactivated human NaV1.7 expressed in HEK293 cells at -20 mV holding potential after 5 mins by IonWorks electrophysiology methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2020
Entry Details Article
PubMed