BDBM50269059 (1S,2S,5S)-N-hydroxy-2-(4-(3-isopropylphenyl)piperidine-1-carbonyl)-5-(2-oxo-2-(piperidin-1-yl)ethyl)cyclohexanecarboxamide::CHEMBL496829

SMILES CC(C)c1cccc(c1)C1CCN(CC1)C(=O)[C@H]1CC[C@H](CC(=O)N2CCCCC2)C[C@@H]1C(=O)NO

InChI Key InChIKey=ZABUEZYWKJKVJI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50269059   

TargetMatrix metalloproteinase-9(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50269059((1S,2S,5S)-N-hydroxy-2-(4-(3-isopropylphenyl)piper...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50269059((1S,2S,5S)-N-hydroxy-2-(4-(3-isopropylphenyl)piper...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50269059((1S,2S,5S)-N-hydroxy-2-(4-(3-isopropylphenyl)piper...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MMP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50269059((1S,2S,5S)-N-hydroxy-2-(4-(3-isopropylphenyl)piper...)
Affinity DataIC50: 67nMAssay Description:Inhibition of HER2 extracellular domain sheddase activity in human BT474 cells after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50269059((1S,2S,5S)-N-hydroxy-2-(4-(3-isopropylphenyl)piper...)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant ADAM10More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Incyte

Curated by ChEMBL
LigandPNGBDBM50269059((1S,2S,5S)-N-hydroxy-2-(4-(3-isopropylphenyl)piper...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human MMP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed