BDBM50268668 6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9H-purine-2-carbonitrile::CHEMBL524619

SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccccc3)nc(nc12)C#N

InChI Key InChIKey=XPRAVWVEAFPXFC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50268668   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California

Curated by ChEMBL
LigandPNGBDBM50268668(6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9...)
Affinity DataIC50: 700nMAssay Description:Inhibition of Trypanosoma brucei rhodesiense rhodesainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50268668(6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human liver cathepsin LMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin B(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50268668(6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of human liver cathepsin BMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed