BDBM50268599 CHEMBL4078066

SMILES COc1cc2CCN(CCn3cc(COc4ccccc4C(=O)Nc4ccc(OC(F)(F)F)cc4)nn3)Cc2cc1OC

InChI Key InChIKey=HMFHTSHKRKYNII-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268599   

TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268599(CHEMBL4078066)
Affinity DataIC50: 4.52E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed