BDBM50268580 CHEMBL4074079

SMILES COc1cc2CCN(CCn3cc(COc4ccccc4C(=O)Nc4ccc(C)cc4)nn3)Cc2cc1OC

InChI Key InChIKey=VBZMWGPVWJHSCM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268580   

TargetATP-dependent translocase ABCB1(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50268580(CHEMBL4074079)
Affinity DataIC50: 7.65E+3nMAssay Description:Inhibition of ABCB1 in human K562/A02 cells assessed as potentiation of adriamycin-induced cytotoxicity by measuring ADR IC50 at 5 uM measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2020
Entry Details Article
PubMed