BDBM50268322 6'-(methylsulfonyl)-N-((trans)-2-phenylcyclopropyl)spiro[azepane-4,2'-chroman]-1-carboxamide::CHEMBL482637
SMILES CS(=O)(=O)c1ccc2OC3(CCc2c1)CCCN(CC3)C(=O)N[C@H]1C[C@@H]1c1ccccc1
InChI Key InChIKey=JXGJTODYQBRZDL-UHFFFAOYSA-N
Data 9 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50268322
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Activity at Cav 1.2 channelMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 49nMAssay Description:Inhibition of rat soluble epoxide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human microsomal epoxide hydrolaseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Human)
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Voltage-gated sodium channel subunit alpha Nav1.5More data for this Ligand-Target Pair
Affinity DataIC50: 3nMAssay Description:Inhibition of human soluble epoxide hydrolase in HEK293 cells assessed as DHET productionMore data for this Ligand-Target Pair