BDBM50267987 (+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]ethyl)amino)-2-hydroxypropyl]oxy)benzonitrile::CHEMBL504479

SMILES COc1ccc(CC(C)(C)NCC(O)COc2ccccc2C#N)cc1

InChI Key InChIKey=KCCUCFUQSYGPBH-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50267987   

TargetBeta-2 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 21nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-3 adrenergic receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataEC50:  20nMAssay Description:Binding affinity to beta3 adrenoceptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 21nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 36nMAssay Description:Binding affinity to CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 300nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 300nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 3.50E+3nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50267987((+/-)-2-([3-((1,1-Dimethyl-2-[4-(methyloxy)phenyl]...)
Affinity DataIC50: 140nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed