BDBM50267972 (S)-3-Amino-4-(1H-imidazol-4-yl)-1-phenyl-butan-2-one; dihydrochloride::(S)-3-amino-4-(1H-imidazol-4-yl)-1-phenylbutan-2-one dihydrochloride::CHEMBL500316

SMILES N[C@@H](Cc1cnc[nH]1)C(=O)Cc1ccccc1

InChI Key InChIKey=YFUSCYGKGZNGMO-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50267972   

TargetHistidinol dehydrogenase(Brucella suis)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50267972((S)-3-Amino-4-(1H-imidazol-4-yl)-1-phenyl-butan-2-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of Brucella suis histidinol dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50267972((S)-3-Amino-4-(1H-imidazol-4-yl)-1-phenyl-butan-2-...)
Affinity DataIC50: 100nMAssay Description:Inhibition of Brassica oleracea (cabbage) histidinol dehydrogenase pre-incubated for 10 min before substrate histidinol addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article

TargetHistidinol dehydrogenase(Brucella suis)
University of Montpellier

Curated by ChEMBL
LigandPNGBDBM50267972((S)-3-Amino-4-(1H-imidazol-4-yl)-1-phenyl-butan-2-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of Brucella suis histidinol dehydrogenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
LigandPNGBDBM50267972((S)-3-Amino-4-(1H-imidazol-4-yl)-1-phenyl-butan-2-...)
Affinity DataKi:  7.60nMAssay Description:Inhibition of Brassica oleracea (cabbage) histidinol dehydrogenase pre-incubated for 10 min before substrate histidinol addition by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2010
Entry Details Article