BDBM50267246 CHEMBL4069303

SMILES CC(C)CC(c1c(O)c2C=CC(C)(C)Oc2c(C(C)=O)c1O)c1c(O)c2C=CC(C)(C)Oc2c(C(C)=O)c1O

InChI Key InChIKey=MAOJOOVKZCEFJE-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267246   

TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267246(CHEMBL4069303)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2020
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267246(CHEMBL4069303)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2020
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267246(CHEMBL4069303)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2020
Entry Details Article
PubMed