BDBM50267244 CHEMBL4077368

SMILES [#6]-[#8]-c1c(-[#6]\[#6]=[#6](\[#6])-[#6])c(-[#8])c(-[#6](-[#6]-[#6](-[#6])-[#6])-c2c(-[#8])c(-[#6](-[#6])=O)c(-[#8])c3-[#6]-[#6](-[#8])C([#6])([#6])[#8]-c23)c(-[#8])c1-[#6](-[#6])=O

InChI Key InChIKey=YBGLZRAVTBFPRS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50267244   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267244(CHEMBL4077368)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 5-LO in human peripheral blood neutrophils using arachidonic acid as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2020
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267244(CHEMBL4077368)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human A549 cell microsomal membrane-derived mPGES-1 assessed as reduction in conversion of PGH2 to PGE2 preincubated for 15 mins follow...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2020
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50267244(CHEMBL4077368)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli MV1190 using arachidonic acid as substrate preincubated for 10 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2020
Entry Details Article
PubMed