BDBM50266967 CHEBI:66678::CHEMBL3393621

SMILES Oc1ccccc1C(=O)c1[nH]c(Cl)c(Cl)c1-n1c(Cl)c(Cl)cc1C(=O)c1ccccc1O

InChI Key InChIKey=QYPJBTMRYKRTFG-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50266967   

LigandPNGBDBM50266967(CHEMBL3393621 | CHEBI:66678)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of biotinylated Bim BH3 peptide binding to GST-tagged mouse Mcl-1 expressed in Escherichia coli BL21 (DE3) pre-incubated for 1 hr followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2020
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50266967(CHEMBL3393621 | CHEBI:66678)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of biotin labelled Bid-BH3 binding to C-terminal GST-tagged human BCL-XL transmembrane domain expressed in Escherichia coli BL21 (DE3) pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed
LigandPNGBDBM50266967(CHEMBL3393621 | CHEBI:66678)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of biotin labelled Bid-BH3 binding to N-terminal truncated 151/C-terminal truncated of 23 residues GST-tagged mouse MCL1 expressed in Esch...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2020
Entry Details Article
PubMed
LigandPNGBDBM50266967(CHEMBL3393621 | CHEBI:66678)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of biotinylated Bim BH3 peptide binding to GST-tagged mouse MCL1 expressed in Escherichia coli BL21 (DE3) incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Hunan Provinc

Curated by ChEMBL
LigandPNGBDBM50266967(CHEMBL3393621 | CHEBI:66678)
Affinity DataIC50: 8.00E+4nMAssay Description:Inhibition of biotinylated Bim BH3 peptide binding to GST-tagged human Bcl-xl expressed in Escherichia coli BL21 (DE3) incubated for 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
LigandPNGBDBM50266967(CHEMBL3393621 | CHEBI:66678)
Affinity DataKi:  10nMAssay Description:Inhibition of MCl-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed