BDBM50266793 CHEMBL4078119

SMILES COCCNC(=O)c1cccc(Oc2cc(CN)ccn2)c1

InChI Key InChIKey=SGFRMAJUABLCJY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266793   

TargetProtein-lysine 6-oxidase(Human)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266793(CHEMBL4078119)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266793(CHEMBL4078119)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human LOXL2 expressed in human whole blood assessed as reduction of H2O2 production from oxidative deamination of DAP prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266793(CHEMBL4078119)
Affinity DataIC50: 290nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266793(CHEMBL4078119)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed