BDBM50266790 CHEMBL4096173

SMILES NCc1ccnc(Oc2ccc(cc2)C(=O)Nc2ccccc2)c1

InChI Key InChIKey=FPKWXZXFSKOCNZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50266790   

TargetProtein-lysine 6-oxidase(Human)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266790(CHEMBL4096173)
Affinity DataIC50: 5.50E+3nMAssay Description:Inhibition of human LOX expressed in HEK cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs foll...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266790(CHEMBL4096173)
Affinity DataIC50: 750nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266790(CHEMBL4096173)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of recombinant human LOXL2 expressed in human whole blood assessed as reduction of H2O2 production from oxidative deamination of DAP prein...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed
TargetLysyl oxidase homolog 2(Human)
Pharmakea Therapeutics

Curated by ChEMBL
LigandPNGBDBM50266790(CHEMBL4096173)
Affinity DataIC50: 270nMAssay Description:Inhibition of human LOXL2 expressed in CHO cells assessed as reduction of H2O2 production from oxidative deamination of DAP preincubated for 2 hrs fo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2020
Entry Details Article
PubMed