BDBM50266524 CHEMBL4068220

SMILES C[C@H]1CN(C[C@@H](C)O1)c1nc(N2CCOCC2)c2sc(cc2n1)-c1ccc(N)nc1

InChI Key InChIKey=VWAPFXOEOXOOSM-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266524   

TargetSerine/threonine-protein kinase mTOR(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50266524(CHEMBL4068220)Copy SMILESCopy InChI

Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end residues) expressed in baculovirus infected Sf21 insect cells assessed as re...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/16/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50266524(CHEMBL4068220)Copy SMILESCopy InChI

Affinity DataIC50: 165nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged PI3K p110alpha/p85alpha expressed in baculovirus using PIP2 as substrate after 1 hr...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/16/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL