BDBM50266518 CHEMBL4071083

SMILES C[C@H]1CN(C[C@@H](C)O1)c1nc(N2CCOCC2)c2sc(cc2n1)-c1ccn[nH]1

InChI Key InChIKey=CCDCSUFMDNCKDI-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50266518   

TargetSerine/threonine-protein kinase mTOR(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50266518(CHEMBL4071083)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end residues) expressed in baculovirus infected Sf21 insect cells assessed as re...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50266518(CHEMBL4071083)
Affinity DataIC50: 175nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using PIP2 as substrate after 1 hr by kinase-glo luminescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50266518(CHEMBL4071083)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human His-tagged PI3K p110gamma expressed in baculovirus using PIP2 as substrate after 1 hr by kinase-glo luminescence assa...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50266518(CHEMBL4071083)
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant full length human N-terminal His6-tagged PI3K p110delta/p85alpha expressed in baculovirus infected Sf21 cells using PIP2 as...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50266518(CHEMBL4071083)
Affinity DataIC50: 15nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged PI3K p110alpha/p85alpha expressed in baculovirus using PIP2 as substrate after 1 hr...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50266518(CHEMBL4071083)
Affinity DataIC50: 15nMAssay Description:Inhibition of P13Kalpha (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandPNGBDBM50266518(CHEMBL4071083)
Affinity DataIC50: 16nMAssay Description:Inhibition of mTOR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails
PubMed