BDBM50266489 CHEMBL4065390

SMILES C1CN(CCO1)c1nc(N2CCOCC2)c2sccc2n1

InChI Key InChIKey=WZDSAEDQRWUJTE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266489   

TargetSerine/threonine-protein kinase mTOR(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50266489(CHEMBL4065390)Copy SMILESCopy InChI

Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant human N-terminal FLAG-tagged mTOR (1362 to end residues) expressed in baculovirus infected Sf21 insect cells assessed as re...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails Article
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TargetPhosphatidylinositol 3-kinase regulatory subunit alpha/4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
West China Hospital of Sichuan University

Curated by ChEMBL

LigandBDBM50266489(CHEMBL4065390)Copy SMILESCopy InChI

Affinity DataIC50: 1.88E+3nMAssay Description:Inhibition of full length recombinant human N-terminal His-tagged PI3K p110alpha/p85alpha expressed in baculovirus using PIP2 as substrate after 1 hr...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
Copy reaction URL