BDBM50266373 2-chloro-5-nitro-N-(pyridin-4-yl)benzamide::CHEMBL510698

SMILES [O-][N+](=O)c1ccc(Cl)c(c1)C(=O)Nc1ccncc1

InChI Key InChIKey=FRPJSHKMZHWJBE-UHFFFAOYSA-N

Data  5 IC50

PDB links: 8 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50266373   

TargetPeroxisome proliferator-activated receptor gamma(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50266373(2-chloro-5-nitro-N-(pyridin-4-yl)benzamide | CHEMB...)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human PPARgamma receptor expressed in Saccharomyces cerevisiae AH109 co-transfected with mouse CBP assessed as inhibition of r...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor delta(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50266373(2-chloro-5-nitro-N-(pyridin-4-yl)benzamide | CHEMB...)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human PPARdelta assessed as effect on TIPP-703-induced activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPeroxisome proliferator-activated receptor gamma(Human)
Graduate School of The Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50266373(2-chloro-5-nitro-N-(pyridin-4-yl)benzamide | CHEMB...)
Affinity DataIC50: 4.70nMAssay Description:Inverse agonist activity at human PPARgamma expressed in CHO cells co-expressing GAL4-NHR-LBD assessed as transcriptional repression preincubated for...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha(Human)
Institute of Mit and Harvard

Curated by ChEMBL
LigandPNGBDBM50266373(2-chloro-5-nitro-N-(pyridin-4-yl)benzamide | CHEMB...)
Affinity DataIC50: 2.95E+3nMAssay Description:Agonist activity at human PPARalpha expressed in CHO cells co-expressing GAL4-NHR-LBD assessed as transcriptional activation preincubated for 6 hrs f...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetPeroxisome proliferator-activated receptor delta(Human)
Okayama University

Curated by ChEMBL
LigandPNGBDBM50266373(2-chloro-5-nitro-N-(pyridin-4-yl)benzamide | CHEMB...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inverse agonist activity at human PPARdelta expressed in CHO cells co-expressing GAL4-NHR-LBD assessed as transcriptional repression preincubated for...More data for this Ligand-Target Pair
In DepthDetails
PubMed