BDBM50266331 CHEMBL458437::N2-(4-(4-isopropylpiperazin-1-yl)-2-methoxyphenyl)-N4-(quinolin-6-yl)-7H-pyrrolo[2,3-d]pyrimidine-2,4-diamine

SMILES COc1cc(ccc1Nc1nc(Nc2ccc3ncccc3c2)c2cc[nH]c2n1)N1CCN(CC1)C(C)C

InChI Key InChIKey=CKDMLWHRLPFYKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50266331   

TargetInsulin-like growth factor 1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266331(N2-(4-(4-isopropylpiperazin-1-yl)-2-methoxyphenyl)...)
Affinity DataIC50: 773nMAssay Description:Inhibition of IGF1R phosphorylation by cellular assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50266331(N2-(4-(4-isopropylpiperazin-1-yl)-2-methoxyphenyl)...)
Affinity DataIC50: 13nMAssay Description:Inhibition of IGF1RMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2012
Entry Details Article
PubMed