BDBM50265895 CHEMBL4097537

SMILES COc1nn(-c2ccccn2)c2cc(ccc12)-c1ccc(cc1)[C@H]1C[C@@H]1C(O)=O

InChI Key InChIKey=BKBCOLUTTHSRPO-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50265895   

TargetFree fatty acid receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50265895(CHEMBL4097537)
Affinity DataEC50:  470nMAssay Description:Agonist activity at human GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2020
Entry Details Article
PubMed
LigandPNGBDBM50265895(CHEMBL4097537)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of phosphodiesterase 4D (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50265895(CHEMBL4097537)
Affinity DataEC50:  410nMAssay Description:Agonist activity at mouse GPR120 expressed in CHO-FlpIn cells after 15 mins by DMR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50265895(CHEMBL4097537)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mouse GPR40 expressed in HEK293 cells assessed as increase in intracellular calcium level after 5 mins by FLUO-4-AM dye-based FLI...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/12/2020
Entry Details Article
PubMed