BDBM50265676 CHEMBL495962::N-(2-(4-Amino-2-oxo-1,2-dihydroquinolin-3-yl)-1H-benzo[d]imidazol-6-yl)-2-(dimethylamino)-N-methylacetamide

SMILES CN(C)CC(=O)N(C)c1ccc2nc([nH]c2c1)-c1c(N)c2ccccc2[nH]c1=O

InChI Key InChIKey=WNVADWMUVOLRPY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50265676   

TargetPlatelet-derived growth factor receptor beta(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265676(N-(2-(4-Amino-2-oxo-1,2-dihydroquinolin-3-yl)-1H-b...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human recombinant PDGFRbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265676(N-(2-(4-Amino-2-oxo-1,2-dihydroquinolin-3-yl)-1H-b...)
Affinity DataIC50: 29nMAssay Description:Inhibition of human recombinant VEGFR2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetFibroblast growth factor receptor 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50265676(N-(2-(4-Amino-2-oxo-1,2-dihydroquinolin-3-yl)-1H-b...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human recombinant FGFR1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed