BDBM50265356 3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-1-phenylpropyl 3-phenylpropanoate::CHEMBL443649

SMILES Fc1ccc(cc1)N(CCCN1CCN(CCC(OC(=O)CCc2ccccc2)c2ccccc2)CC1)c1ccc(F)cc1

InChI Key InChIKey=HMGVPHBFARTUCU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50265356   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50265356(3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin...)
Affinity DataKi:  36.6nMAssay Description:Displacement of [3H]WIN-35428 from DAT in rat striatum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50265356(3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin...)
Affinity DataKi:  235nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50265356(3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin...)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]citalopram from SERT in rat brain stem membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50265356(3-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin...)
Affinity DataKi:  5.35E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat frontal cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed