BDBM50264998 CHEMBL4103458

SMILES CC(C)C[C@@H](NC(C)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCCN)C(=O)NCc1ccc(cc1)C(N)=N

InChI Key InChIKey=UFNWIBYSOUCSGW-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50264998   

TargetProprotein convertase subtilisin/kexin type 6(Human)
University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50264998(CHEMBL4103458)
Affinity DataKi:  4.90nMAssay Description:Inhibition of recombinant human PACE4 expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2020
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 6(Human)
University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50264998(CHEMBL4103458)
Affinity DataKi:  4.90nMAssay Description:Inhibition of recombinant human PACE4 expressed in S2 insect cells using pyroGlu-Arg-Thr-Lys-Arg-AMC peptide as substrate after 1 hr by spectrofluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetProprotein convertase subtilisin/kexin type 6(Human)
University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50264998(CHEMBL4103458)
Affinity DataKi:  4.90nMAssay Description:Inhibition of recombinant human PACE4 using pGlu-Arg-Thr-Lys-Arg-AMC peptide as substrate by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed
TargetFurin(Human)
University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50264998(CHEMBL4103458)
Affinity DataKi:  9.80nMAssay Description:Inhibition of recombinant human furin expressed in drosophila S2 cells using pyrGlu-Arg-Thr-Lys-Arg-7-amido-4-methylcoumarin as substrate after 60 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2020
Entry Details Article
PubMed
TargetFurin(Human)
University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50264998(CHEMBL4103458)
Affinity DataKi:  9.80nMAssay Description:Inhibition of recombinant human furin expressed in S2 insect cells using pyroGlu-Arg-Thr-Lys-Arg-AMC peptide as substrate after 1 hr by spectrofluoro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetFurin(Human)
University of Gdansk

Curated by ChEMBL
LigandPNGBDBM50264998(CHEMBL4103458)
Affinity DataKi:  9.80nMAssay Description:Inhibition of recombinant human furin using pGlu-Arg-Thr-Lys-Arg-AMC peptide as substrate by spectrofluorometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed