BDBM50264786 CHEMBL4100640

SMILES OC(=O)CC1CCC2(CC1)CCN(CC2)c1ccc(cn1)-c1nc2cc(ccc2[nH]1)C(F)(F)F

InChI Key InChIKey=HMTQTKXSPAGAQJ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50264786   

TargetDiacylglycerol O-acyltransferase 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50264786(CHEMBL4100640)
Affinity DataIC50: 6nMAssay Description:Inhibition of human DGAT1 expressed in yeast membrane fraction assessed as inhibition of triglyceride formation using diolein/oleoyl-CoA as substrate...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50264786(CHEMBL4100640)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50264786(CHEMBL4100640)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of MK499 binding to human ERGMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50264786(CHEMBL4100640)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50264786(CHEMBL4100640)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of PXR (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed