BDBM50264743 (S)-1-(4-(3-(bis(4-fluorophenyl)amino)propyl)piperazin-1-yl)-3-phenylpropan-2-yl propionate::CHEMBL490424

SMILES CCC(=O)O[C@H](CN1CCN(CCCN(c2ccc(F)cc2)c2ccc(F)cc2)CC1)Cc1ccccc1

InChI Key InChIKey=MZRKRGQEXLPPNW-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50264743   

TargetSodium-dependent dopamine transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50264743((S)-1-(4-(3-(bis(4-fluorophenyl)amino)propyl)piper...)
Affinity DataKi:  15.1nMAssay Description:Displacement of [3H]WIN-35428 from DAT in rat striatum membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50264743((S)-1-(4-(3-(bis(4-fluorophenyl)amino)propyl)piper...)
Affinity DataKi:  81.8nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50264743((S)-1-(4-(3-(bis(4-fluorophenyl)amino)propyl)piper...)
Affinity DataKi:  1.04E+3nMAssay Description:Displacement of [3H]citalopram from SERT in rat brain stem membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed
TargetTransporter(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50264743((S)-1-(4-(3-(bis(4-fluorophenyl)amino)propyl)piper...)
Affinity DataKi:  1.36E+3nMAssay Description:Displacement of [3H]nisoxetine from NET in rat frontal cortex membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMed