BDBM50264482 CHEMBL4086748

SMILES COC(=O)CNC(=O)c1cnc2c(SSc3cccc4cc(cnc34)C(=O)NCC(=O)OC)cccc2c1

InChI Key InChIKey=KWDAVAFOLMHSLD-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50264482   

TargetSTAM-binding protein(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50264482(CHEMBL4086748)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of AMSH (unknown origin) using DiUbK63TAMRA as substrate by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target26S proteasome non-ATPase regulatory subunit 14(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50264482(CHEMBL4086748)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in human erythrocytes using Ub4-pepOG protein substrate preincubated ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target26S proteasome non-ATPase regulatory subunit 14(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50264482(CHEMBL4086748)
Affinity DataIC50: 300nMAssay Description:Inhibition of 26S proteasome regulatory subunit RPN11 deubiquitinating activity in beta5 inhibitor MG132 pretreated human HeLa cells expressing UbG76...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCOP9 signalosome complex subunit 5(Human)
University of California San Diego

Curated by ChEMBL
LigandPNGBDBM50264482(CHEMBL4086748)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of CSN5 (unknown origin) using SCFskp2-Nedd8OG as substrate after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed