BDBM50263540 (R)-1-(1-(3,5-difluorophenyl)-3-(methylamino)propyl)-7-fluoro-3,3-dimethylindolin-2-one::CHEMBL446809

SMILES CNCC[C@@H](N1C(=O)C(C)(C)c2cccc(F)c12)c1cc(F)cc(F)c1

InChI Key InChIKey=IJZRPGINHKPXPE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263540   

TargetSodium-dependent noradrenaline transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50263540((R)-1-(1-(3,5-difluorophenyl)-3-(methylamino)propy...)
Affinity DataIC50: 6nMAssay Description:Inhibition of norepinephrine uptake at human NET expressed in MDCK cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50263540((R)-1-(1-(3,5-difluorophenyl)-3-(methylamino)propy...)
Affinity DataIC50: 330nMAssay Description:Inhibition of serotonin uptake at human SERT expressed in JAR cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed