BDBM50263000 2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(phenylsulfonyl)acetamide::CHEMBL446349

SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3ccccc3c2n1Cc1ccccc1

InChI Key InChIKey=OPNVDNPKPOZEDE-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50263000   

TargetPhospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2, membrane associated(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 90nMAssay Description:Inhibition of mouse group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IID secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human group2D phospholipase A2 by [3H]oleic acid-labeled Escherichia coli membrane assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IID secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse group2D phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IIE secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IIE secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 48nMAssay Description:Inhibition of mouse group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IIF secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup IIF secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2 group V(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPhospholipase A2 group V(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 70nMAssay Description:Inhibition of mouse group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup 10 secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetGroup 10 secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50263000(2-(1-benzyl-2-ethyl-1H-6,7-benzoindol-4-yloxy)-N-(...)
Affinity DataIC50: 35nMAssay Description:Inhibition of mouse group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed