BDBM50262844 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-indol-4-yloxy)acetic acid::CHEMBL504813

SMILES CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1

InChI Key InChIKey=WCOSWMKQOOTINK-UHFFFAOYSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50262844   

TargetPhospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 580nMAssay Description:Inhibition of mouse group1B phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2, membrane associated(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse group2A phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup IID secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human group2D phospholipase A2 by [3H]oleic acid-labeled Escherichia coli membrane assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup IID secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse group2D phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup IIE secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup IIE secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse group2E phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup IIF secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 550nMAssay Description:Inhibition of human group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup IIF secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse group2F phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2 group V(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPhospholipase A2 group V(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup 10 secretory phospholipase A2(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGroup 10 secretory phospholipase A2(Mouse)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50262844(2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-isobutyl-1H-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of mouse group2X phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed